Leash Biosciences

Overview

Leash Biosciences is a biotechnology company leveraging a unique combination of functional genomics and advanced machine learning to accelerate the discovery and development of small molecule therapeutics. Their platform is designed to identify novel modulators for complex or historically 'undruggable' protein targets by understanding how genes and proteins function within specific cellular contexts.

The platform integrates high-throughput biological data, such as that derived from CRISPR-based screens, with computational models to find relationships between genetic perturbations, cellular phenotypes, and small molecule activity. This approach allows Leash Biosciences to uncover novel drug targets, identify active compounds with desired functional effects, and predict optimal molecular structures and properties, aiming to deliver effective drug candidates more efficiently than traditional methods.

Key Features

• AI/ML-driven drug discovery platform
• Integration of functional genomics data (e.g., CRISPR screens)
• Focus on challenging or undruggable protein targets
• Identification of small molecule modulators with functional effects
• Predictive modeling of compound activity and properties
• High-throughput screening integration

Supported Platforms

• Web Browser